Chromatrap®’s Positive Primer Set 5 recognises the promoter region of the protein-coding FkBP5 gene that has roles in glucocorticoid and progestin signalling pathways. It can regulate prostrate physiology in the presence of androgen (Magee et al. 2013). An 81 base pair fragment is amplified with this primer set.
It is a positive gene target for the male hormone receptor gene AR (Androgen Receptor) in the presence of testosterone.