Research reagents for the detection of antibodies in animal sera by ELISA. Each ELISA plate is coated with Minute Virus of Mice (MVM) Parvovirus strain Crawford: a purified inactivated whole organism propagated in L cells. Will cross react with other Parvovirus.
Minute Virus of Mouse is a single stranded DNA virus of the family Parvoviridae, genus Parvovirus. The virus is nonenveloped, roughly spherical with a diameter of 20-25 nm. There are no pathological changes associate with MVM, however mice infected in less than a few days from birth can develop fatal disease. This virus is very common in laboratory mice. It is highly infectious in nature and spreads by urine and feces of acutely infected mice by the nasal-oral route. Aerosol transmission is rare. Mice, laboratory and wild type, are the only natural hosts of MVM.
National Research Council (US) Committee on Infectious Diseases of Mice and Rats. Infectious Diseases of Mice and Rats. Washington (DC): National Academies Press (US); 1991.
Baker DG. Natural pathogens of laboratory mice, rats, and rabbits and their effects on research. Clin Microbiol Rev. 1998;11:231–266.
Waggie, Kimberly S. Manual of Microbiologic Monitoring of Laboratory Animals. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Center for Research Resources, 1994.