Research reagents for the detection of antibodies in animal sera by ELISA. Each ELISA plate is coated with mouse Adenovirus (MAV) strain Florida: a purified inactivated whole virus propagated in NIH 3T3 cells and mouse Adenovirus (MAV) Adenovirus strain K87: a purified inactivated whole virus propagated in NBM cells. Will cross react with other Adenovirus.
Mouse adenoviruses are double stranded DNA viruses of the family Adenoviridae, genus Mastadenovirus. The virus is a nonenveloped, regular icosahedron with a diameter of 70-90 nm. Two strains of mouse adenoviruses are known, FL-1 (MAd-1) and K87(MAd-2). Transmission of the virus occurs through close or direct contact. FL-1 can be shed in urine, and K87 can be shed in feces. Experimental infection of suckling mice causes necrosis of the kidney, heart, spleen, and brain. Mice and rats appear to be the only hosts of the viruses.
National Research Council (US) Committee on Infectious Diseases of Mice and Rats. Infectious Diseases of Mice and Rats. Washington (DC): National Academies Press (US); 1991.
Baker DG. Natural pathogens of laboratory mice, rats, and rabbits and their effects on research. Clin Microbiol Rev. 1998;11:231–266.
Waggie, Kimberly S. Manual of Microbiologic Monitoring of Laboratory Animals. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Center for Research Resources, 1994.