Research reagents for the detection of antibodies in animal sera by ELISA. Each ELISA plate is coated with Cilia-Associated Respiratory Bacillus (CARB) Bacillus strain Animal isolate: a purified inactivated whole organism propagated in NBM cells.
Cilia-associated respiratory bacillus (CARB) is a gram-negative, rod-shaped bacillus of unknown classification. Transmission occurs through direct contact with infected animals. CARB is usually a copathogen, most commonly with M. pulmonis, but can cause disease alone in mice and rats. CARB infection causes lesions in the upper and lower respiratory tract, and pathology associated with infection is usually that of M. pulmonis. Hosts of the virus include mice, rats, and rabbits. Other laboratory rodents, such as guinea pigs and hamsters, have been experimentally infected.
Schoeb, T. R., et al. “Pathogenicity of Cilia-Associated Respiratory (CAR) Bacillus Isolates for F344, LEW, and SD Rats.” Veterinary Pathology, vol. 34, no. 4, 1997, pp. 263–270., doi:10.1177/030098589703400401.
National Research Council (US) Committee on Infectious Diseases of Mice and Rats. Infectious Diseases of Mice and Rats. Washington (DC): National Academies Press (US); 1991.
Baker DG. Natural pathogens of laboratory mice, rats, and rabbits and their effects on research. Clin Microbiol Rev. 1998;11:231–266.
Waggie, Kimberly S. Manual of Microbiologic Monitoring of Laboratory Animals. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Center for Research Resources, 1994.