SKU: IM-055C Category:


Research reagents for the detection of antibodies in animal sera by ELISA. Each ELISA plate is coated with Lactate dehydrogenase elevating virus (LDV): a recombinant nucleocapsid protein (VP1).

Additional information

Weight 22.4 oz
Dimensions 8.5 × 5.25 × 3 in
Storage Temperature


Shipping Temperature


Unit Quantity

96 Control Wells and 96 Control Antigen Wells

XpressBio 2-Plate Insert
XpressBio 2-Plate Insert Spanish

Background Info

Lactate Dehydrogenase Elevating Virus (LDV) is a single stranded RNA virus of the family Togaviridae. Transmission occurs through contaminated tumors, cells, or serum in experimental procedures, but can also occur by direct contact via blood and saliva. The most notable pathological change due to LDV infection is an increase in lactate dehydrogenase in serum. Other pathological changes include reduction in thymus weight, and progressive limb paralysis. Elevated lactate dehydrogenase levels in serum and low-level virus titers can persist for life. Mice are the only hosts of the disease.

National Research Council (US) Committee on Infectious Diseases of Mice and Rats. Infectious Diseases of Mice and Rats. Washington (DC): National Academies Press (US); 1991.

Baker DG. Natural pathogens of laboratory mice, rats, and rabbits and their effects on research. Clin Microbiol Rev. 1998;11:231–266.

Waggie, Kimberly S. Manual of Microbiologic Monitoring of Laboratory Animals. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Center for Research Resources, 1994.