Mouse Streptobacillus moniliformis ELISA Kit


SKU: IM-061C Category:


Research reagents for the detection of antibodies in animal sera by ELISA.  Each ELISA plate is coated with antigen from a purified inactivated whole virus propagated in Streptobacillus medium.

Additional information

Weight 22.4 oz
Dimensions 8.5 × 5.25 × 3 in
Storage Temperature


Shipping Temperature


Unit Quantity

96 Antigen Wells 96 Control Antigen Wells

XpressBio 2-Plate Insert
XpressBio 2-Plate Insert Spanish

Background Info

Streptobacillus moniliformis is a gram-negative bacterium of the family Leptotrichiaceae. It can cause the disease commonly referred to as Rat Bite Fever in humans. The natural host for this bacterium is rats, who will carry the disease in their respiratory tract and middle ear and often show no symptoms. The disease can then be transmitted via aerosols, fomites, or saliva to mice, humans, guinea pigs, and others. Early infection in mice can cause septic lymphadenitis and death. Prolonged cases in surviving mice can result in chronic polyarthritis. In humans, infection causes fever, rash, and polyarthralgias and untreated cases can result in patient death.

Elliott, S. P. “Rat Bite Fever and Streptobacillus Moniliformis.” Clinical Microbiology Reviews, vol. 20, no. 1, 2007, pp. 13–22., doi:10.1128/cmr.00016-06.

Wullenweber, Michael. “Streptobacillus Moniliformis-a Zoonotic Pathogen. Taxonomic Considerations, Host Species, Diagnosis, Therapy, Geographical Distribution.” Laboratory Animals, vol. 29, no. 1, 1995, pp. 1–15., doi:10.1258/002367795780740375.

Eisenberg, Tobias, et al. “Phylogenetic and Comparative Genomics of the Family Leptotrichiaceae and Introduction of a Novel Fingerprinting MLVA for Streptobacillus Moniliformis.” BMC Genomics, vol. 17, no. 1, 2016, doi:10.1186/s12864-016-3206-0.

National Research Council (US) Committee on Infectious Diseases of Mice and Rats. Infectious Diseases of Mice and Rats. Washington (DC): National Academies Press (US); 1991.