Description
Xpress Capture Protein G Coated Microplates provide a solid-phase surface for capturing immunoglobulins through affinity interactions between immobilized Protein G and the Fc region of compatible antibodies. Fc-directed capture helps position the antigen-binding regions away from the plate surface so they remain available to bind target molecules in solution.
Protein G binds immunoglobulins in a species-, class-and subclass-dependent manner. It commonly binds IgG from mouse, rat, rabbit, human, and several other mammalian species and often provides broader binding to mouse and rat IgG subclasses than Protein A. Compatibility should be confirmed for the antibody used in the assay.
The plates are intended for research immunoassays in which an immobilized antibody captures a labeled or otherwise detectable antigen. Detection may be performed with enzyme-labeled, biotinylated, fluorescent, chemiluminescent, or comparable reagents.
