Each plate is coated with Clostridium piliforme (Tyzzer’s Disease, Cpil) Clostridium strain Animal isolate: a purified inactivated whole organism propagated in BS-C-1 cells
Weight |
2 oz |
Dimensions |
8 × 5.25 × 0.75 in |
Storage Temperature |
+4C
|
Shipping Temperature |
RT
|
Unit Quantity |
48 Antigen Wells and 48 Control Antigen Wells
|
For Research Use Only. Not for Diagnostic Use.
Background Info
Clostridium piliforme is a gram-negative bacterium responsible for the disease commonly called Tyzzer’s disease. Tyzzer’s disease has a high prevalence in laboratory colonies likely due to its wide range of host species and moderately contagious nature. Transmission is through the fecal-oral route, as the bacterium is relatively unstable in environmental conditions. Infection begins in the ileum and cecum. The organisms then ascend to the liver and finally infect other tissues including the myocardium. Tyzzer’s disease has been reported in many countries worldwide.
National Research Council (US) Committee on Infectious Diseases of Mice and Rats. Infectious Diseases of Mice and Rats. Washington (DC): National Academies Press (US); 1991.
Baker DG. Natural pathogens of laboratory mice, rats, and rabbits and their effects on research. Clin Microbiol Rev. 1998;11:231–266.
Waggie, Kimberly S. Manual of Microbiologic Monitoring of Laboratory Animals. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Center for Research Resources, 1994.