Each plate is coated with Lymphocytic Choriomeningitis Virus (LCM) Arenavirus strain Armstrong: The antigen is a purified inactivated whole virus propagated in L cells.
||8 × 5.25 × 0.75 in
48 Antigen Wells and 48 Control Antigen Wells
Lymphocytic Choriomeningitis Virus (LCMV) is a single stranded RNA virus of the family Arenaviridae, genus Arenavirus. Mice and hamsters host and transmit the virus, and many other animals are susceptible including humans, monkeys, dogs, rats and guinea pigs. Shedding of the virus occurs in the urine, saliva, and milk. Post-natal infection of mice can result in complete recovery or death within a few weeks without any symptoms of disease. Infection of mice in utero or within a few days of birth will result in lifelong shedding, growth retardation, eventual immune complex glomerulonephritis, and occasionally death. Human prenatal infection can be deadly and will almost always adversely affect brain function.
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Waggie, Kimberly S. Manual of Microbiologic Monitoring of Laboratory Animals. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Center for Research Resources, 1994.
“Lymphocytic choriomeningitis virus: an underrecognized cause of neurologic disease in the fetus, child, and adult” Seminars in pediatric neurology vol. 19,3 (2012): 89-95.