Each plate is coated with mouse Hepatitis Virus (MHV) Coronavirus strain JHM-Thermostable: a purified inactivated whole virus propagated in 17CL-1 Cells. It will cross with other MHV strains and other Coronavirus.
||8 × 5.25 × 0.75 in
48 Antigen Wells and 48 Control Antigen Wells
Mouse Hepatitis Virus refers to a large group of single stranded RNA viruses of the family Coronaviridae, genus Betacoronavirus. The virus is an enveloped RNA virus of pleomorphic shape, roughly 80-160 nm in diameter. MHV is extremely contagious. Mode of transmission is primarily aerosol, direct contact, and fomites, with experimental transmission possible via transplantable tumors. Infection usually presents with lesions in various organs and necrosis of the liver and lymphoid tissue. Mice are the only natural carriers of MHV, although rats have been shown to have the ability to carry the disease.
National Research Council (US) Committee on Infectious Diseases of Mice and Rats. Infectious Diseases of Mice and Rats. Washington (DC): National Academies Press (US); 1991.
Baker DG. Natural pathogens of laboratory mice, rats, and rabbits and their effects on research. Clin Microbiol Rev. 1998;11:231–266.
Waggie, Kimberly S. Manual of Microbiologic Monitoring of Laboratory Animals. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Center for Research Resources, 1994.