Each plate is coated with Polyoma (poly) Papovirus strain PRA-111: The antigen is a purified inactivated whole virus propagated in NBM cells.
||8 × 5.25 × 0.75 in
48 Antigen Wells and 48 Control Antigen Wells
Polyoma virus is a nonenveloped DNA virus of the family Papovaviridae, genus Polyomavirus. The virus is highly contagious, and is shed in urine, saliva, and feces. Transmission most commonly occurs through the respiratory tract via aerosols or infected food and bedding. Mice are the only natural hosts of the virus. The most notable pathological change due to polyoma virus infection is the development of tumors, although this does not usually occur in natural infection. Tumors have been reportedly induced in experimental infection of hamsters, rats, guinea pigs and three other unnatural hosts. Tumor lines, virus stocks, and other biologicals should be screened for contamination with polyoma virus.
National Research Council (US) Committee on Infectious Diseases of Mice and Rats. Infectious Diseases of Mice and Rats. Washington (DC): National Academies Press (US); 1991.
Waggie, Kimberly S. Manual of Microbiologic Monitoring of Laboratory Animals. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Center for Research Resources, 1994.