Each plate is coated with Coronavirus: Mouse Hepatitis Virus is used as a surrogate for RCV/SDA.
||8 × 5.25 × 0.75 in
48 Antigen Wells and 48 Control Antigen Wells
Rat Coronavirus/Sialodacryoadenitis virus (RCA/SDA) is a single stranded RNA virus of the family Coronaviridae, genus Coronavirus. It is a very common virus in laboratory rats and is extremely contagious. Spreading can occur easily through direct contact or aerosols. Infection lasts for about a week and will continue in a colony until all rats develop immunity. Naïve rats are more susceptible to develop infection of the respiratory tract and inflammation and necrosis of the salivary and lacrimal glands. Infection of RCA/SDA can increase host susceptibility to other pathogens, or complicate studies involving the eyes, salivary glands, lacrimal glands, respiratory tract or immune system.
National Research Council (US) Committee on Infectious Diseases of Mice and Rats. Infectious Diseases of Mice and Rats. Washington (DC): National Academies Press (US); 1991.
Baker DG. Natural pathogens of laboratory mice, rats, and rabbits and their effects on research. Clin Microbiol Rev. 1998;11:231–266.
Waggie, Kimberly S. Manual of Microbiologic Monitoring of Laboratory Animals. U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Center for Research Resources, 1994.