Research reagents for the detection of antibodies in animal sera by ELISA. Each ELISA plate is coated with Toolan’s Virus (H1) Parvovirus strain Toolan: The antigen is a purified inactivated whole virus propagated in NBHa cells. Will cross react with other Parvovirus
Toolan’s H-1 virus is a small, nonenveloped single stranded DNA virus of the family Parvoviridae, genus Parvovirus. Transmission of H-1 occurs by exposure to infectious milk, urine, nasal secretions, and feces. Natural infection of H-1 does not appear to cause disease, and H-1 has little interference on laboratory research. Pathological changes due to this virus arise from its infection of replicating cells, causing cell lysis, and thus damage to the liver. Laboratory and wild rats are the only natural hosts of H-1 virus.
Baker DG. Natural pathogens of laboratory mice, rats, and rabbits and their effects on research. Clin Microbiol Rev. 1998;11:231–266.
National Research Council (US) Committee on Infectious Diseases of Mice and Rats. Infectious Diseases of Mice and Rats. Washington (DC): National Academies Press (US); 1991.