Description
The Sovicell TRANSIL HSA Binding Kit estimates the binding of drugs to human serum albumin (HSA) and predicts the plasma protein binding. The assay kit measures the dissociation constant (KD) of drugs to albumin and hence allows the calculation of albumin binding even under disease and physiological states that alter the albumin content of human serum. In combination with our TRANSIL AGP Binding Kit it is possible to obtain accurate prediction of plasma protein binding in a highly controlled and reproducible assay environment. Internal quality controls provide easy assessment of recovery, experiment and data quality.
Additional information
Weight |
22.4 oz |
Dimensions |
11.2 × 4.6 × 6.2 in |
Unit Quantity |
96 well, 240 ul
|
Shipping Temperature |
+4C
|
Storage Temperature |
-20C
|
For research use only. not for diagnostic use.
Citations
Interaction of pharmaceutical metabolites with blood proteins and membrane lipids in the view of bioconcentration: A preliminary study based on in vitro assessmentAuthors: Kowalska, Dorota, et al.
Science of the Total Environment 783 (2021)
Development of an orally delivered GLP-1 receptor agonist through peptide engineering and drug delivery to treat chronic diseaseAuthors: Pechenov, Sergei, et al.
Scientific Reports 11.1 (2021): 22521
In Vitro Potency and Preclinical Pharmacokinetic Comparison of All-D-Enantiomeric Peptides Developed for the Treatment of Alzheimer’s DiseaseAuthors: Schartmann, Elena, et al.
Journal of Alzheimer's disease 64.3 (2018): 859-873
Comparison of blood-brain barrier penetration efficiencies between linear and cyclic all-d-enantiomeric peptides developed for the treatment of Alzheimer's diseaseAuthors: Schartmann, Elena, et al.
European journal of pharmaceutical sciences 114 (2018): 93-102
Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacyAuthors: Ravishankar, Divyashree, et al.
Scientific reports 7.1 (2017): 1-16
Preclinical Pharmacokinetic Studies of the Tritium Labelled D-Enantiomeric Peptide D3 Developed for the Treatment of Alzheimer´s DiseaseAuthors: Jiang, Nan, et al.
PloS one 10.6 (2015): e0128553
New Serotonin 5-HT1A Receptor Agonists Endowed with Antinociceptive Activity in VivoAuthors: Valhondo, Margarita, et al
Journal of medicinal chemistry 56.20 (2013): 7851-7861
High-Throughput 1,536-Well Fluorescence Polarization Assays for α1-Acid Glycoprotein and Human Serum Albumin BindingAuthors: Yasgar, Adam, et al.
PLoS ONE 7(9): e45594
Interactions of Poly(amidoamine) Dendrimers with Human Serum Albumin: Binding Constants and MechanismsAuthors: Giri, Jyotsnendu, et al
Acs Nano 5.5 (2011): 3456-3468