Description
The Sovicell TRANSIL Intestinal Absorption kit measures the affinity of drugs to phosphatidylcholine membranes. It is not only a screening tool to predict intestinal permeability coefficients, but also to predict compounds’ tissue binding. As drug-membrane interactions are key to both the process of membrane permeability and to binding to and permeating into the cell membranes of tissues the assay kit is an ideal tool to predict intestinal permeability rates as well as the volume of distribution early in drug discovery phase. Internal quality controls provide easy assessment of recovery, experiment and data quality.
Additional information
Weight |
22.4 oz |
Dimensions |
11.2 × 4.6 × 6.2 in |
Unit Quantity |
96 well, 240 ul
|
Shipping Temperature |
+4C
|
Storage Temperature |
-20C
|
For research use only. not for diagnostic use.
Citations
Aquatic toxicity, bioaccumulation potential, and human estrogen/androgen activity of three oxo-Liquid Organic Hydrogen Carrier (oxo-LOHC) systemsAuthors: Seol, Yohan, et al.
Journal of Hazardous Materials, Volume 476, 2024
Electrocatalytic water treatment of per- and polyfluoroalkyl substances reduces adsorbable organofluorine and bioaccumulation potentialAuthors: Lin, Zunhui, et al.
RSC Adv. 2024 May 14;14(22):
A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (fu,cell)Authors: Treyer, Andrea, et al.
Pharmaceutical research 36.12 (2019): 178
Intracellular Drug Bioavailability: Effect of Neutral Lipids and PhospholipidsAuthors: Treyer, Andrea, et al.
Molecular pharmaceutics 15.6 (2018): 2224-2233
Screening the baseline fish bioconcentration factor of various types of surfactants using phospholipid binding dataAuthors: Droge, Steven TJ, et al.
Environmental Science: Processes & Impacts 23.12 (2021): 1930-1948
Membrane–water partition coefficients to aid risk assessment of perfluoroalkyl anions and alkyl sulfatesAuthors: Droge, Steven TJ
Environmental science & technology 53.2 (2018): 760-770
Sorption of Cationic Surfactants to Artificial Cell Membranes: Comparing Phospholipid Bilayers with Monolayer Coatings and Molecular SimulationsAuthors: Timmer, Niels, and Steven TJ Droge
Environmental Science & Technology 51.5 (2017): 2890-2898.